Polyethylenimine (PEI)-assisted transfection is a mainstay in upstream processing (USP) for viral vector manufacturing. But recent developments are shifting it from a ...

Successful production of high titers of adeno-associated virus (AAV) vector at a large scale is a race against time. During AAV manufacturing, a transfection complex made up of plasmid DNA (pDNA) and ...

In his laboratory at the University of Poitiers in France, Abderrazak El Albani contemplates the rock glittering in his hands. To the untrained eye, the specimen resembles a piece of golden tortellini ...

Wholesale food distributor Sirna & Sons Produce of Ravenna plans to lay off 45 workers from its distribution facility in Norwalk. The company disclosed the planned layoffs, scheduled for December, in ...

AbbVie is paying ADARx Pharmaceuticals $335 million upfront to secure options on next-gen small interfering RNA (siRNA) therapeutics across several disease areas. The collaboration and license option ...

The ADARx Pharmaceuticals partnership, which could be worth “several billion dollars” in the end, adds to AbbVie’s existing work in the space after the $1.4 billion acquisition of Aliada Therapeutics ...

Chronic hepatitis B (CHB) remains a significant global health burden, with existing therapies including nucleos(t)ide analogs, interferon, siRNA, and therapeutic vaccines demonstrating limited success ...

Introduction: Apigenin, a natural flavonoid with well-established antioxidant, anticancer, and anti-inflammatory activities, has recently attracted attention for its pigmentation-promoting effects.

An inferiority complex involves feelings of inadequacy and insecurity that stem from a real or imagined deficiency. It may lead to effects such as withdrawal and aggression. The American Psychological ...

Transfection is a crucial non-viral technique for introducing DNA or RNA into cells, yet achieving high efficiency and consistency can be challenging, particularly with difficult cell types.