Heterochromatin, sometimes known as the “dark side of the genome,” is a poorly studied fraction of DNA that makes up about half of our genetic material. For more than 50 years scientists have puzzled ...

The new study reveals a remarkable way that cells keep us safe from transposable elements (TEs) gone wild. The researchers found that cells have taken advantage of an entire protein network to repress ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Heterochromatin, a key component of the ...

A recent study In Press at the Journal of Cell Biology reports that herpes simplex virus 1 (HSV-1) exploits heterochromatin to successfully exit the nucleus. The heterochromatin markers macroH2A1 and ...

Toxicologists have found that the protein p53 continuously protects our cells from tumorigenesis by coordinating important metabolic processes that stabilize their genomes. The gene coding for the ...

Department of Bioengineering, University of Illinois at Urbana−Champaign, 1102 Everitt Lab, 1406 W. Green Street, Urbana, Illinois 61801, United States Biomedical Research Center, Mills Breast Cancer ...

Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel ...

A long-standing puzzle in evolution is why new genes — ones that seem to arise out of nowhere — can quickly take over functions essential for an organism’s survival. A new study in fruit flies may ...

Department of Molecular Genetics, Institute of Cellular Physiology, National Autonomous University of Mexico, Mexico City, Mexico Heterochromatin is a constituent of eukaryotic genomes with functions ...

Some rare people may essentially be able to cure themselves of HIV infections. Twice, people infected with HIV have had levels of the virus in their bodies drop to undetectable levels after bone ...