gut.bmj

“DPP- 4 inhibitor alleviates gut-brain axis Parkinson’s disease pathology” - can dipeptidyl peptidase 4 inhibitors be repurposed as disease-modifying drugs for body-first ...

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Medscape

GLP-1s Cut Dementia Risk vs DPP-4 in Dialysis Patients

The initiation of GLP-1 agonists was associated with a lower risk for Alzheimer’s disease and related dementias than the initiation of DPP-4 inhibitors in patients with diabetes undergoing ...
Daily

Bi-Weekly Cofrogliptin Outperforms Daily DPP-4 Inhibitors in Type 2 Diabetes: Phase 2 Trial

China: A new multicenter phase 2 clinical trial, published in Diabetes, Obesity and Metabolism, suggests that cofrogliptin, administered once every two weeks, could offer an effective and ...
Cochrane

Does treatment with DPP-4 inhibitors prevent complications for people with chronic kidney disease and type 2 diabetes?

For people with chronic kidney disease (CKD) (long-term damage to the kidneys that reduces their ability to filter blood), also having diabetes (a lifelong condition that causes a person's blood sugar ...
gut.bmj

DPP-4 inhibitor alleviates gut-brain axis pathology in Parkinson’s disease

5 Catholic Kwandong University College of Medicine Department of Medical Science, Gangneung-si, The Republic of Korea Background Dipeptidyl peptidase-4 inhibitors (DPP-4is) have been reported to ...
IEEE

Predicting The Molecular Structure Relationship and The Biological Activity of DPP-4 Inhibitor Using Deep Neural Network with CatBoost Method as Feature Selection

Abstract: Dipeptidyl peptidase 4 (DPP-4) are drug targets for type-2 diabetes mellitus (T2DM). The enzyme dipeptidyl peptidase 4 (DPP-4) can catalyze the decrease in the hormone incretin peptide, ...
finalweapon

Tony Hawk’s Pro Skater 3 + 4 Details Tutorial, Customization and Accessibility Features

Activision and Iron Galaxy revealed new details about the tutorial, customization, and accessibility features in Tony Hawk’s Pro Skater 3 + 4. Those who are dropping in for the first time or returning ...
Scientific Research Publishing

Efficacy of Oral Semaglutide after Switching from DPP-4 Inhibitors on Glucose Level and Body Weight Control in Japanese Type 2 Diabetes Patients with Obesity ()

1 OKM Okamoto Internal Medicine Clinic, Tokyo, Japan. 2 Department of General Medicine, Juntendo University Faculty of Medicine, Tokyo, Japan. GLP-1 receptor agonists (GLP-1 RAs), which exogenously ...
IEEE

An overview of possible Inhibitors of DPP-4 protein and their essential roles in the management of diabetes mellitus

Abstract: Incorporation of DPP4 inhibitors to the list of various insulinotropic drugs used to manage Type 2 diabetes mellitus (T2DM) is regarded as a significant advancement in the field of novel ...
C&EN

Upregulation of the PI3K/AKT and Nrf2 Pathways by the DPP-4 Inhibitor Sitagliptin Renders Neuroprotection in Chemically Induced Parkinson’s Disease Mouse Models

International Clinical Research Centre, St. Anne’s University Hospital Brno (FNUSA-ICRC), Brno 60200, Czech Republic Department of Physiology, Faculty of Medicine, Masaryk University, Kamenice 753/5, ...
healthday

Depression Risk Lower With GLP-1 Receptor Agonists Versus DPP-4 Inhibitors in Seniors

MONDAY, Feb. 24, 2025 (HealthDay News) -- For older adults with type 2 diabetes (T2D), use of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) is associated with a modestly lower risk for ...
BioWorld

CSPC wins China clearance of new DPP-4 inhibitor

CSPC Pharmaceutical Group Ltd. on Jan. 13 gained the National Medical Products Administration’s approval of Shanzeping (prusogliptin tablets; DBPR-108) as a novel oral dipeptidyl peptidase-IV (DPP-4) ...