Gene therapy is a promising technique for the treatment of a wide range of diseases at the genetic level, addressing the root cause of many subsequent disorders. Recent advancements have facilitated ...

Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) comes with a heavy quality-of-life burden that doesn't ...

After decades of research, gene therapy is finally on track to deliver solutions to myriad diseases once considered untreatable. More than 400 gene therapy trials are currently underway in the United ...

Gene delivery vehicles have helped realize the concept of treating human diseases by introducing normal alleles of genes into appropriate target cells. These gene delivery vehicles include recombinant ...

Several quality attributes (QAs) must be monitored to ensure an effective and safe final product when developing adeno-associated virus (AAV) vectors as drug products. Thermal stability, aggregate ...

A Navy investigation into the deadly sinking of a Marine Corps amphibious assault vehicle last year found leadership confusion, poor communications and gaps in training. But ultimately the service ...

Researchers at Oregon Health and Science University have used mouse models to estimate the frequency at which gene therapies delivered by adeno-associated virus (AAV) vectors integrated into host DNA, ...

Marines with Marine Rotational Force Europe 21.1 (MRF-E), Marine Forces Europe and Africa, conduct a live-fire range using Assault Amphibious Vehicles (AAV) in Blatindan, Norway, March 16, 2021. US ...

Marines with Marine Rotational Force-Europe 21.1, Marine Forces Europe and Africa, conduct a safety of use memorandum (SOUM) on an assault amphibious vehicle in preparation for Exercise Reindeer II, ...