NFL Week 16 picks against spread
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NFL Week 16 is here, so let's look at the odds and make some picks and predictions for the coming weekend as the playoffs near.
There are just three games left in the 2025 NFL regular season, and there are still playoff spots up for grabs. Not only that, but the teams already in the post
Now, he's going up against a Jets defense that just allowed Trevor Lawrence to post six total touchdowns (five passing and one rushing), which led to the firing of defensive coordinator Steve Wilks. Shough shouldn't face much resistance this week, which could make it very hard for undrafted rookie Brady Cook to keep up in his second career start.
We make picks for all 16 NFL games with levels of confidence ahead of Week 16. We’re a week away from Christmas and the NFL playoff race is reaching a fevered pitch. We won’t know every playoff spot after this weekend, but we could see most of the playoff berths locked up by the close of 49ers-Colts on Monday.
Experts from around the NFL make their picks for a Week 16 game between the New York Giants and Minnesota Vikings.
In Week 15, there were four games with double-digit spreads, and 44-year-old Philip Rivers helped lead his team to the only cover among those underdogs. He's already a betting spread legend.