ESPN's FPI simulation projects how the 49ers finish the 2025 season, their playoff seed, and how far San Francisco advances.

Jones had both the highest completion percentage (69.6 percent) and yards per attempt (7.4) of his career during that stretch ...

San Francisco 49ers wide receiver Ricky Pearsall missed the team's first practice of the week because of injuries to his knee ...

Could A.J. Brown be the answer to the San Francisco 49ers' wide receiver needs in 2026? We look at the trade possibilities.

The San Francisco 49ers announced a minor roster move on Tuesday, releasing cornerback Isaiah Bolden from the practice squad.

The last time the Colts and 49ers played was in the 2021 season, when the Colts defeated San Francisco on the road by a score ...

One prominent NFL insider named two teams that could potentially be interested in trading for San Francisco 49ers QB Mac ...

The 49ers need plenty more of that in the final stretch as not only do they face better defenses but much better offenses.

That is, until now. Eddy Pineiro has been revolutionary for the 49ers and has been key to the 49ers' success this season.

Monday, 8:15 p.m. EST, ESPN. BetMGM NFL odds: 49ers by 6. Against the spread: 49ers 9-5; Colts 8-6. Series record: Colts lead ...

As the Indianapolis Colts look to keep their playoff hopes alive, up next for them is a home matchup with the San Francisco ...

Two teams that could be interested? The Pittsburgh Steelers and Indianapolis Colts. The Steelers will likely be looking to ...