The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both ...

Cedars-Sinai scientists have created a new experimental drug called TY1 that helps the body repair damaged DNA and restore ...

Cancer research, drug safety testing and aging biology may all gain a major boost from a new fluorescent sensor developed at Utrecht University. This new tool allows scientists to watch DNA damage and ...

A new fluorescent sensor is giving scientists an unprecedented view of how cells respond to DNA damage, capturing the repair process as it unfolds in real time. The tool, developed at Utrecht ...

An international research team has identified a human protein, ANKLE1, as the first DNA-cutting enzyme (nuclease) in mammals ...

Scientists have created a live-cell DNA sensor that reveals how damage appears and disappears inside living cells, capturing the entire repair sequence as it unfolds. Instead of freezing cells at ...

Cedars-Sinai researchers have created TY1, an experimental RNA-based drug that helps the body repair damaged DNA and restore injured tissue. The idea came from studying tiny molecular “messages” ...

TY1 enhances the action of TREX1, a gene that helps immune cells clear damaged DNA, helping to minimize scar tissue post heart attacks.

New Houston Methodist research has revealed that a protein associated with neurodegenerative diseases such as dementia and amyotrophic lateral sclerosis (ALS) also plays a role in regulating DNA ...