RNase II is a ubiquitous exoribonuclease that processively hydrolyses RNA in the 3′ to 5′ direction, releasing 5′ monophosphates 1. The enzyme binds RNA and in the presence of divalent cations cleaves ...
This is a preview. Log in through your library . Abstract Based on a recent ternary complex crystal structure of human DNA polymerase β with a G:A mismatch in the active site, we carried out a ...