University of Pittsburgh School of Medicine and UPMC Hillman Cancer Center scientists have discovered a novel subset of cancer-fighting immune cells that reside outside of their normal neighborhood – ...

T-bet expression is required for persistence of memory B cells that have rapid differentiation potential to become antibody-producing plasma cells in response to a second infection BIRMINGHAM, Ala. – ...

At the surface, the immune response to a flu virus is simple. Some cells recognize the pathogen and send a signal to the immune system, and immune cells produce a potentially lifesaving antibody ...

The mechanism underlying how seasonal allergies recur year after year with precise timing remains largely unknown. An international team led by Professor Rudolf Valenta has identified a specific type ...

If you've been hopping between arms for booster shots, a new study suggests that your lymph nodes remember exactly where you first got jabbed and perform far better when you return to that same arm.

Getting measles doesn’t confer benefits on the immune system — in fact, it’s just the opposite. Even a mild case of measles destroys the memory cells that confer resistance on bugs the patient has ...

Immune cells called B cells make antibodies that fight off invading bacteria, viruses and other foreign substances. During their preparation for this battle, B cells transiently revert to a more ...

Researchers have uncovered a critical, previously underappreciated role for B cells in vaccine protection. Best known for producing antibodies, B cells also guide other immune cells, specifically CD8 ...