TERC is a lncRNA with 451nt that functions as the template for telomerase during telomere lengthening. Several studies showed that TERC also functions as a lncRNA independent of telomerase, such as ...

Much the way the caps on the ends of a shoelace prevent it from fraying, telomeres — regions of repetitive DNA sequences and a protein structure — protect the tips of chromosomes from damage. Every ...

Telomere shortening is a potential diagnostic tool for differentiating ILD types, particularly in idiopathic pulmonary fibrosis (IPF). Genetic mutations in telomerase genes, such as TERC and TERT, ...

A case-cohort study was conducted involving 291 NWTS-5 registrants. Telomerase activity was measured using the telomeric repeat amplification protocol (TRAP). Expression levels of TERT mRNA (encoding ...

Much the way the caps on the ends of a shoelace prevent it from fraying, telomeres - regions of repetitive DNA sequences and a protein structure - protect the tips of chromosomes from damage. Every ...

A randomized study of platinum based chemotherapy with or without amifostine for the treatment of children with hepatoblastoma (HB): A report of the Intergroup Hepatoblastoma Study P9645 This is an ...

In a recent study published in the journal Nature Communications, researchers discovered a family with a germline-encoded telomere template sequence mutation (TTAGGT) in telomerase, which results in a ...