Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) is a hereditary small vessel disease primarily caused by mutations in the NOTCH3 gene. These ...

CARASIL, or cerebral autosomal-recessive arteriopathy with subcortical infarcts and leukoencephalopathy is a rare genetic disorder following the autosomal recessive inheritance pattern. Maeda et al.

Future Neurology. 2008;3(6):683-704. Qing Miao, Department of Pathology, Turku University, Turku, Finland. qinmia@utu.fi Saara Tikka, Protein Chemistry Unit ...

About The Study: The findings of this study suggest the NOTCH3-associated small vessel disease (NOTCH3-SVD) staging system will help to better harmonize NOTCH3-SVD and cerebral autosomal dominant ...