We found a class of lamina I spinothalamic tract (STT) neurons selectively excited by iontophoretic histamine. The responses of this class of neurons parallel the pure itching sensation this stimulus ...

Itch is relieved by scratching, but the neural mechanisms that are responsible for this are unknown. Spinothalamic tract (STT) neurons respond to itch-producing agents and transmit pruritic ...

Deep brain stimulation (DBS) for motor disorders such as Parkinson’s Disease (PD) and Essential Tremor has advanced significantly with the introduction of directional DBS leads and pulse generators ...