In the 1940s, scientists at the recently established National Cancer Institute were trying to breed mice that could inform our understanding of cancer, either because they predictably developed ...

Ribosome profiling is a deep-sequencing-based tool that allows the detailed measurement of translation globally and in vivo. The method provides quantification of levels of new protein synthesis, as ...

Researchers have developed a new microscopy technique to observe how ribosomes function in cells. With this method, they can monitor individual ribosomes as they convert mRNA into proteins. The ...

Ribosomes are molecular machines that translate messenger RNA (mRNA), which is transcribed from DNA, into proteins. Scientists have now learned more about ribosomes in nature, and their function. This ...

Last year, the Nobel Prize in Chemistry heralded work on DNA transcription, a cornerstone process in molecular biology in which a cell synthesizes a messenger RNA (mRNA) version of genomic DNA. For ...