Thus, our studies revealed regulatory mechanisms of glycolysis-driven cellular senescence by AUF1-mediated decay of PGAM1 and PDP2 mRNAs.” "Thus, our studies revealed regulatory mechanisms of ...

“We believe our study utilizing Single-Cell RNA sequencing will provide additional rationale towards the effects on APC treatment observed in previous studies on 5xFAD AD mice.” “In our investigation, ...

Northwestern Medicine scientists have discovered how molecular "traffic controllers" in cells influence aging and cellular senescence—a state where cells stop dividing but remain metabolically active.

Recent breakthroughs in anti-aging research have opened up exciting possibilities for extending human healthspan. Scientists worldwide are uncovering innovative treatments that target the underlying ...

Researchers found that the body’s natural recycling system, the lysosome, plays a vital role in removing the protein that drives premature aging. When this system breaks down, aging speeds up. By ...

Within each cell, there is a constant struggle between life-sustaining molecules and molecules that could hasten its demise. For the first time, scientists have created a molecule that can identify ...

As life expectancy continues to climb globally, the focus of many people has moved from longevity alone to living in good health. This has drawn attention to the need to extend "healthspan," the ...

Ask a friend what DNA is and, chances are, they have a general idea. Seventy years after scientists discovered the two-stranded helix, DNA (deoxyribonucleic acid) is widely understood as the keeper of ...