In the early and mid-1980s, scientists used phages to express recombinant proteins. The protein was retained inside the virions, so screening required growing viral plaques, creating a stamp of these ...
An international study led by researchers from the Department of Medicine and Life Sciences (MELIS) of Pompeu Fabra University and Stanford University (California) has designed a system to identify ...
In a recent study posted to the bioRxiv* preprint server, researchers performed a ProP-PD (proteomic peptide phage display) analysis to identify peptides from intrinsically disordered human (host) ...
When a person receives a cancer diagnosis, treatment can often include chemotherapy. This method of treating cancer also can affect healthy cells. But what if there was a drug on the market that, ...
A microdialysis-captured peptide can enter the cells. The cells have been cultured in a dish, and the peptide found in the microdialysis screening (green marker) has been added to the culture medium.
Aga2-fusion protein binding to yeast cell by Aga1. Image provided by Invitrogen. Phage display systems, reviewed in a recent issue of The Scientist, 1 have proven enormously useful for the detection ...
A team at the University of Macau aimed to develop a novel peptide targeting the tumor necrosis factor (TNF)-TNFR2 interaction as a selective regulatory T cell (Treg) stimulator. Through phage display ...