"Our study reveals there is a dialogue occurring between the gut microbes and the body that is vital for regulating bile acid ...

Synthesized in the liver, bile acids play diverse roles in digestion and metabolism. However, when their processes are disrupted, disease can occur. Scientists seek advanced technologies to better ...

The VDR is a member of the steroid/hormone nuclear receptor superfamily that includes 48 ligand-activated transcription factors. [3] These factors bind to conserved elements in the promoters of genes ...

BBPH, bear bile powder high dose; BBPL, bear bile powder low dose; DSS, dextran sulfate sodium; NC, normal control; 5-ASA, 5-Amino salicylic acid. Ulcerative colitis (UC) is a chronic autoimmune ...

Inflammation and scarring of the bile ducts—also known as cholangiopathies—can stop the bile from flowing, a vital fluid that helps digest fats. When bile can’t move through these ducts, it backs up ...

There are several types of surgery for bile duct cancer, which are meant to cure cancer or to manage its symptoms. Your bile ducts transport bile from the liver and the gallbladder to the small ...

Bile reflux occurs when bile, a liquid that the liver makes, flows back up into the stomach or the esophagus. It may be a sign of an underlying condition or a complication of certain surgical ...

Beneficial gut microbes and the body work together to fine-tune fat metabolism and cholesterol levels, according to a new preclinical study by investigators from Weill Cornell Medicine and the Boyce ...