Nitric oxide gets neurons together. And it seems to do it backward. Work by Nikonenko et al. suggests that a protein called PSD-95 prompts nitric oxide release from postsynaptic dendritic spines, ...

The structure and function of synapses are highly heterogeneous, even among synapses formed on single neuron 1,2,3. At the same time, pre- and postsynaptic structures and functions are well ...

This is a preview. Log in through your library . Abstract The activity-dependent regulation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors and the ...

Bolstering disintegrating neural connections may help boost brainpower in Alzheimer's disease patients. Researchers zeroed in on the enzymes that manipulate a key scaffolding protein for synapses, the ...

Scientists have discovered that SynGAP and PSD-95, two abundance proteins in PSD that are known to cause autism when mutated, can form an autonomously assembled network structure both in test-tube and ...

The ability of synapses to strengthen or weaken, form anew, or disappear entirely underlies the brain’s capacity to establish functional neuronal circuits during development and to learn and remember ...

All neurons in our brain are wired via a micron-sized connection unit called synapse, and each synapse contains a layer of densely-packed, protein rich compartment called postsynaptic density (PSD), ...