The 49ers opened the second half with their best drive of the day. Soon after the Titans ruled out three safeties because of injuries, quarterback Brock Purdy capped a four-play, 67-yard drive with a 13-yard scoring strike to receiver Jauan Jennings.

The Steelers took over first place in the AFC North by surviving the Ravens after an overturned touchdown in the final minutes. The Jaguars remain atop the AFC South after dismantling the Colts, who lost Daniel Jones to an Achilles injury. And the Bills all but dashed the Bengals' playoff hopes with a 39-34 win in the snow.

The Seattle Seahawks defeated the Los Angeles Rams, 38-37 in overtime, in the first game of Week 16 to take over the top spot in the division and conference with a 12-3 record. It featured a 457-yard,

As if this game needed a further testimonial as to its gravitas, the Rams (+310) and the Seahawks (+650) are currently the two favorites to win the Super Bowl (the Broncos sit third at +850). Each is 8-1 in their last nine games.