This rare genetic disorder can affect your nerves and cause tumors on the brain and spinal cord that may impact hearing, vision, and balance. Proper treatment and regular monitoring can help manage ...

This review will discuss the contribution of merlin loss of function in NF2-related tumors and common human cancers and the molecular mechanisms that lead to tumorigenesis, tumor progression or ...

Neurofibromatosis type 2 is caused by a change in the NF2 gene located on chromosome 22. This gene encodes a protein known as merlin. Mutations in the NF2 gene disrupt the function of merlin, which is ...

Neurofibromatosis type 2 is most often diagnosed based on the presence of physical symptoms that are part of the specific diagnostic criteria for the disorder. Genetic testing for the NF2 mutation is ...

Neurofibromatosis is a group of rare genetic disorders that cause benign tumors to form on nerve tissue. Tumors in this disorder are usually noncancerous (benign), but can sometimes become cancerous ...

The proteins that provide cells with a sense of personal space could lead to a therapeutic target for neurofibromatosis type 2 (NF2), an inherited cancer disorder, according to researchers. Their ...

For patients with NF2-related schwannomatosis and progressive tumors, the ALK inhibitor brigatinib (Alunbrig) was associated with radiographic response for multiple tumor types, as well as ...

Safety and Efficacy of CT041 in Patients With Refractory Metastatic Pancreatic Cancer: A Pooled Analysis of Two Early-Phase Trials VEGFR1 and VEGFR2 peptides were injected subcutaneously into ...

Randomized phase II study of rituximab, methotrexate (MTX), procarbazine, vincristine, and cytarabine (R-MPV-A) with and without low-dose whole-brain radiotherapy (LD-WBRT) for newly diagnosed primary ...