Multiple sclerosis (MS) is a condition that affects your brain and spinal cord. It damages the myelin sheath, the tissue that surrounds and protects your nerve cells. This damage blocks or slows down ...

The development of treatment for multiple sclerosis over the past 25 years is a success of translational medicine. In this Timeline article, Tintore et al. chart major developments and discuss the ...

Multiple sclerosis can affect many areas of your daily life, including dental care. Symptoms of multiple sclerosis and the medications you take for these symptoms can lead to an increased need for ...

The CD40–CD40L costimulatory pathway regulates adaptive and innate immune responses and has been implicated in the pathogenesis of multiple sclerosis. Frexalimab is a second-generation anti-CD40L ...

Richard M. Ransohoff is at Third Rock Ventures, Boston, Massachusetts 02116, USA, and in the Department of Cell Biology, Harvard Medical School, Boston. Each of the multiple-sclerosis treatments ...

Multiple sclerosis (MS) is a chronic, disabling, inflammatory disease that damages your nerves. People with MS may live roughly seven years less than the general population, with an average life ...