For more than a century, Alzheimer’s disease has been framed as irreversible. Once memory and thinking decline, recovery has ...

More clinically relevant mouse models for neurodegenerative diseases are sorely needed as tools to study disease progression and to develop future therapeutics. At last month's virtual International ...

For over a century, Alzheimer's disease (AD) has been considered irreversible. Consequently, research has focused on disease ...

Scientists reversed advanced Alzheimer's in mice using a compound that restores cellular energy. The breakthrough challenges ...

Alzheimer’s researchers have long wished for better mouse models. That is now coming true. Scientists at the Jackson Laboratory in Bar Harbor, Maine, are cranking out numerous lines that express ...

Myotonic dystrophy type 1 (DM1) is the most common form of adult-onset muscular dystrophy, affecting about 1 in 8,000 people.

Clinicians and researchers have suspected for years that an aggressive, less-common form of multiple sclerosis (MS) is likely a distinct form of the disease. Now, new research conducted using a more ...

Mouse models of neurodevelopmental disorders possess unique, sex-specific metabolic dysfunctions, according to a new study in eNeuro. Understanding the unique metabolic effects of each disorder in ...

A team of biostatisticians led by University of Pittsburgh School of Public Health scientists report “Transcriptomic congruence analysis for evaluating model organisms” in PNAS that they’ve developed ...

Selecting an appropriate mouse model is one of the most important decisions a pre-clinical researcher can make. Which is best suited for immuno-oncology? Cancer research and drug discovery has changed ...

Researchers generate cutting-edge mouse models by engrafting human cells and tissue into the animals to better study the human immune system. Scientists have employed mouse models in immunological ...