YF550-C1, an E3 ligase inhibitor of CBL-B, to demonstrate T cell and NK cell activation and anti-tumor activities in syngeneic and PDX tumor model. This is an ASCO Meeting Abstract from the 2024 ASCO ...

Pancreatic beta cells (β-cells) reside in a cluster of cells in the pancreas known as the islets of Langerhans. Pancreatic β cells are the only cells that produce insulin - a hormone that decreases ...

Macrophages rely on lysosomes to balance microbial killing with self-protection, generating reactive oxygen and nitrogen species during phagocytosis. Using platinum nanoelectrodes, researchers at ...

Platinum nanoelectrodes measure reactive oxygen and nitrogen species emitted at a macrophage phagocytic cup, revealing how lysosomal pH modulates ROS/RNS flux during frustrated phagocytosis of a glass ...

Shanghai and Suzhou, TOKYO--(BUSINESS WIRE)--Elpiscience Biopharma, Ltd. (Chairman and CEO: Darren Ji, MD, Ph.D., “Elpiscience”) and Astellas Pharma Inc. (TSE ...

Macrophages are white blood cells that play a key role in helping to protect us against microscopic threats, from infections to cancer. These cells constantly survey the body’s tissues and consume ...

Cancer immunotherapy candidate BSI-508, a bispecific fusion molecule targeting PD-1 and CD47, is undergoing early development at Biosion Inc., who recently presented preclinical data on the product.

PALO ALTO, Calif.--(BUSINESS WIRE)--Pheast Therapeutics (“Pheast”), a biotech developing novel macrophage checkpoint therapies to defy cancer, today announced the presentation of new preclinical data ...

SCIENCE CHINA Life Sciences published a research article online by Professor Yanfeng Gao’s team from the School of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University. They designed and ...

SHANGHAI and SUZHOU, China and TOKYO, Dec. 28, 2023 /PRNewswire/ -- Elpiscience Biopharma, Ltd. (Chairman and CEO: Darren Ji, MD, Ph.D., "Elpiscience") and Astellas ...