These parkin knockout (KO) mice were generated by creating a germline disruption in the parkin gene within exon 3 leading to a truncated transcript coding for the first 95 amino acids of mouse parkin ...
Species: Mouse Genes: Gba1 Modification: Gba1: Conditional Knock-out Disease Relevance: Parkinson's Disease Strain Name: B6.129-Gba1 tm1Clk /J Genetic Background: Backcrossed 11 generations to ...