Nipocalimab is a fully human IgG-1 monoclonal antibody that binds to FcRn, resulting in the reduction of circulating IgG levels including pathogenic IgG autoantibodies. 1 The studies established that ...
Biohaven’s first-in-modality extracellular degrader BHV-1300 reduced levels of its immunoglobulin G (IgG) target by up to 43% in an ongoing phase I trial. The two-armed small molecule acts by dragging ...
The most common form of the kidney disease called glomerulonephritis is IgA nephropathy. IgA nephropathy is believed to be caused by IgA1-containing immune complexes formed in the blood that ...
After encapsulated cells secrete human IgG, the fluorescent probes attach to the protein. The combination of Cyto-Cellect ® PLUS and Cyto-Mine ® provides a test for measuring single-cell productivity ...
Injecting antibodies from a healthy person into someone suffering from rheumatoid arthritis can reduce inflammation and slow bone degeneration, but how this occurs has remained largely unknown until ...
BARCELONA -- A drug targeting immunoglobulin G (IgG) currently approved for myasthenia gravis and chronic inflammatory demyelinating polyneuropathy (CIDP) now looks like it could take the rheumatology ...
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