Formation of the energy-producing machinery in the proximal tubule of the nephron is an essential step in differentiation. The authors show that mitochondrial localization depends on LRRK2, the ...

Ancient viruses are embedded everywhere in the human genome. Estimates range, but it's thought that about eight percent of the human genome could be made up of these ancient retroviruses, which are ...

The new platform's ethically grounded approach promises to reveal much about how human embryos form during the earliest stages of pregnancy. It's one of life's most defining moments -- that crucial ...

A lot happens in the first month of human embryo development as a single cell morphs into multitudes. Yet despite its significance, this period is basically a “black box” to researchers, says stem ...

A recent study in Advanced Science presents a method for studying early human embryology by bioprinting epiblast-like structures from human-induced pluripotent stem cells (hiPSCs). The model forms a ...

The team observed the emergence of the three-dimensional embryo-like structures under a microscope in the lab. These started producing blood (seen here in red) after around two weeks of development - ...

A research team showed that, contrary to current models, one early embryonic cell dominates lineages that will become the fetus. “They are not identical,” said Magdalena Zernicka-Goetz, a ...

Our ancient past isn't always buried history. When it comes to our DNA, nearly 9% of the human genome is made up of leftover genetic material from ancient viruses (called endogenous retroviruses or ...

Researchers at the Francis Crick Institute have developed a new stem cell model of the mature human amniotic sac, which replicates development of the tissues supporting the embryo from two to four ...