Using participant skin cells reprogrammed into neurons, Weill Cornell Medicine researchers have identified genetic signatures ...
A Northwestern Medicine study published in Nature Communications has revealed how HIV can protect infected cells by altering the sugars on their surface, hindering the host immune system and avoiding ...
Scientists are testing CRISPR gene editing as a potential HIV cure after successfully removing the virus from infected cells ...
At the cellular level, HIV-1 transmission involves a highly coordinated process whereby the virus binds to CD4 receptors and one of two coreceptors—CCR5 (R5) or CXCR4 (X4)—on host immune cells, ...
Among treatment-naive adults with advanced HIV disease, integrase inhibitors are a preferred first-line therapy over protease inhibitors.
In the last year, over 40 million people in the world were living with human immunodeficiency virus (HIV). In 2024, over a million were diagnosed with HIV and roughly 630,000 died due to HIV-related ...
The chemokine receptors CCR5 and CXCR4 are the two major coreceptors for HIV entry. Numerous efforts have been made to develop a new class of anti-HIV agents that target these coreceptors as an ...
Texas Biomed researchers find that existing treatments control TB and HIV, but the immune system does not revert to normal, ...
The global challenge posed by HIV-1 infection continues to drive research into its underlying mechanisms and the host immune response. Central to this pursuit is the role of T cells, particularly CD4 ...
The ability for HIV to hide in the body in a dormant state makes curing the 40 million people living with the virus a challenge. Researchers at the University of North Carolina at Chapel Hill have ...