Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, No. 18 (May 3, 2022), pp. 1-12 (12 pages) B and T lymphocytes of the adaptive immune system undergo ...
Using drugs that inhibit enzymes called CDK4/6 and CDK2 extends the G1 phase of the cell cycle and helps to slow the growth of drug-resistant breast cancer.
For a cell to progress through the G1 phase of the cell cycle and divide, it must first integrate various signals. It emerges that cells in a ‘primed’ G1 state — characterized by intermediate ...
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