A PICALM gene variant disrupts microglia, the brain’s cleanup cells, reducing their ability to clear harmful proteins and lipids. This dysfunction leads to lipid droplet buildup in microglia, ...
The role of the adapter protein PICALM in the development of Alzheimer's disease is well documented. Researchers from the German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), the German ...
The brain is a special organ, and immune cells there called microglia work to repair damage and maintain the health of neural networks. About ten percent of brain cells are estimated to be microglia, ...
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Gene variant slows down removal of debris in the brain, increasing Alzheimer's risk, say researchers
A type of brain cell that plays a vital role in maintaining neural networks and repairing injuries lies at the core of a promising new study on Alzheimer's disease from the USF Health Byrd Alzheimer's ...
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