Biopharmaceutical production depends on buffers. Making sure the right buffer solutions are available, in the right place on the manufacturing line, at the right time, and in the right quantity, is a ...

Can a Workflow that Is Automated Provide Comparable Results? Buffer preparation and exchange are es-sential steps in the development of biopharmaceuticals. These processes require many manual steps ...

• Various process parameter optimizations were evaluated for the diafiltration buffer, including buffer pH, buffer ionic strength and excipients selection. Optimizing ionic strength of the buffer ...

Real-time, in-process understanding Quantitative monitoring of excipient and protein concentration using a single probe in ultrafiltration/diafiltration operations ...

Buffer exchange is a critical step to developing optimal vectors and payloads. Compared to biologics, development of delivery vectors like lipid nanoparticles (LNPs) and adeno-associated viruses (AAVs ...