Cells have sophisticated methods of sensing stimuli and communicating with nearby cells in response to these stimuli. For example, macrophages can sense environmental stimuli—tissue damage, foreign ...
NEW UNDERSTANDING: Kelvin Cooper predicts an upswing in interest because of new developments like comprehending the cytokine signaling pathway. Biochemical message-routing molecules are being ...
In vitro studies pinpoint signaling pathways that could be potential targets in oral squamous cell carcinoma treatments.
Schematic diagram of the IL-6/JAK/STAT3 signaling pathway activation in mouse liver macrophages. IRs, inhibitory receptors (IRs); ICIs, immune checkpoint inhibitors; IL-6, interleukin-6; ALT, alanine ...
Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...
Zymeworks Inc. has presented new preclinical data for its bispecific molecule ZW1528 targeting IL-4Rα and IL-33, aimed at treating respiratory inflammation such as chronic obstructive pulmonary ...