A study could open new pathways for understanding how cholesterol influences cell membranes and their receptors, paving the way for future research on diseases linked to membrane organization. A new ...

Hyperthermia, a cancer treatment using controlled heat to kill tumor cells, shows promise but faces limitations due to some tumor cells' unexpected heat resistance. Researchers from Japan have now ...

A shift in the balance between two lipids – cholesterol and sphingomyelin – makes hybrid epithelial-mesenchymal cancer cells less responsive to certain chemotherapy drugs.

This is a preview. Log in through your library . Abstract Cholesterol-laden macrophage foam cells are a hallmark of atherosclerosis. For that reason, cholesterol metabolism in macrophages has ...

Michael N. Trinh, Michael S. Brown, Joseph L. Goldstein, Jaeil Han, Gonçalo Vale, Jeffrey G. McDonald, Joachim Seemann, Joshua T. Mendell, Feiran Lu Proceedings of ...

Researchers discover novel targets for bladder cancer therapeutics and demonstrate that a new combination of existing drugs, including statins, blocks tumor growth in mice. Like all cancers, bladder ...

Since the 1990s, scientists have known cholesterol is important in Alzheimer's, but they gained little traction in their efforts to understand the relationship between the lipid and the disease.

A cell membrane is illustrated to show the surface in red. Blue objects are proteins, including ion channels, which can send electrical impulses into cells. Lipids, or fats, are in yellow. In this ...