Tumor necrosis factor related apoptosis inducing ligand (TRAIL) belongs to the Tumor necrosis factor (TNF) family of death-inducing ligands, and signaling downstream of TRAIL ligation to its ...

The enzyme caspase-8 induces a molecular cell death programme called pyroptosis without involving its enzymatic activity, a new study by Hamid Kashkar published in Nature shows. In order to safeguard ...

In animals the process of programmed cell death, or apoptosis, is thought to be mediated by caspases, a family of cysteine proteases that cleave one another and key intracellular proteins, killing the ...

Most unnecessary or dangerous cells such as virus-infected cells commit suicide by activating an in-built suicide program. This type of cell death is referred to as "programmed cell death". Until ...

Caspase Related Reagents Courtesy of Bingren Hu, Queen's Medical Center, Hawaii. Provided by Cell Signaling TechnologyConfocal micrograph of double immunostaining for cleaved caspase-3 (green) and ...

Apoptosis is a carefully regulated process that can be influenced by many factors, and thus tracking and monitoring these processes is a vital and regular part of biological research. Flow cytometry ...

Small cell lung cancer (SCLC) is one of the most aggressive forms of lung cancer, with a five-year survival rate of only five percent. Despite this ...

Small cell lung cancer (SCLC) is one of the most aggressive forms of lung cancer, with a five-year survival rate of only 5%. Despite this poor prognosis, SCLC is initially highly responsive to ...

Expression profiles associated with disease progression in non-small cell lung cancer. Background: Cisplatin is a platinum-based chemotherapeutic drug used for treating a variety of human cancers such ...