Age-related macular degeneration is the most common cause of blindness in Western populations. Susceptibility is influenced by age and by genetic and environmental factors. Complement activation is ...

In degenerative disc disease (DDD), the discs that separate your spine's bones, or vertebrae, start to breakdown, or degenerate. The discs provide cushion between the vertebrae, absorb shock, and ...

Dysregulated complement pathways are linked to progression from iAMD to advanced AMD, including NVAMD and GA. Higher systemic levels of C4, C4b, and a reduction in C3 are associated with increased ...

Degenerative disc disease is a condition in which the intervertebral discs of the spine become weak and start to deteriorate. There can be a multitude of causes for this condition. Fortunately, there ...