Figure 1: Ub/Ubl modifiers have a comparable fold and are activated and conjugated similarly. While the importance of DUBs is well documented, our understanding of DUB substrate specificity and ...

Ever wondered what your liver was for? Worth looking after it! Enzymes! There are tens of thousands of chemical reactions going on inside our bodies all the time. I'm at a farmers' market in Edinburgh ...

Researchers from Queen Mary University of London's School of Biological and Behavioral Sciences, using the simple fission yeast as a model, have shown that the new TOR inhibitor rapalink-1 prolongs ...

Subscribe to our newsletter for the latest sci-tech news updates. Led by Huimin Zhao, a professor of chemical and biomolecular engineering at the U. of I., the team reported its findings in the ...

Epigenetic drug discovery and development programs have attracted much attention and investment in recent years. This is driven by the potential to develop novel therapeutic strategies that can ...

The new study, published in Communications Biology by Juhi Kumar, Kristal Ng and Charalampos Rallis, sheds light on how drugs and natural metabolites can influence lifespan through the Target of ...